https://pierre-ecohealth.co.za/metabolic-support/

Specific compounds are  combined specifically for the synergisms (relationships) between the elements to create a powerful supplement that supports metabolic health

Below is a short synopsis of the synergistic actions contained in the combination of these compounds:

Forskolin 10% and Resveratrol

Forskolin increases intracellular cAMP by activating adenylate cyclase. Resveratrol has been shown to increase cellular cAMP by inhibiting phosphodiesterase (PDE), which breaks down cAMP. Cyclic AMP  controls key metabolic processes.

• SO LETS INCREASE cAMP TO TARGET DISORDERS LIKE:

• Heart failure • Chronic inflammatory diseases • Neurological disorders

This combination has been studied for:

• Reducing intraocular pressure

• Protecting retinal cells from degeneration.

Forskolin 10% and Alpha Lipoic Acid

Forskolin promotes breakdown of stored fat.

ALA acts as a potent antioxidant that enhances mitochondrial function and helps stabilize metabolism, supporting the fat loss process.

Alpha-lipoic acid is known for its role in reducing insulin resistance and improving metabolic parameters.

Forskolin 10% and Ginkgo Biloba Leaf Extract

Forskolin relaxes smooth muscles in blood vessels, while Ginkgo biloba reduces blood viscosity and inhibits platelet aggregation. Combined, they are thought to significantly improve both peripheral and cerebral blood flow.

Ginkgo biloba is known for improving oxygen utilization in the brain, while Forskolin increases intracellular cAMP, which is essential for synaptic plasticity and neuronal survival. This combination is used  to combat cognitive decline and provide neuroprotection.

Alpha Lipoic Acid & Resveratrol

A combination of resveratrol and alpha-lipoic acid (often with vitamins D, B, and folic acid) reduces BMI, improves insulin sensitivity, and helps manage metabolic disturbances in patients with Polycystic Ovary Syndrome (PCOS).

Alpha-lipoic acid (ALA) and resveratrol are potent antioxidants that show promise in treating dry eye disease (DED) by reducing inflammation, protecting corneal cells, and improving tear film stability.

Alpha Lipoic Acid & Ginko Biloba Leaf Extract

ALA is known to:

• Improve nerve conduction

• Reduce symptoms of neuropathic pain.

Ginkgo Biloba enhances this effect by improving nerve blood flow and reducing neuronal damage.

 ALA acts directly, while Ginkgo Biloba is 

• Neuroprotective

• Anti-inflammatory

• Powerful Antioxidant Protecting neurons and supporting healthy blood flow to the brain.

This combination may  combat age-related cognitive  decline.

Ginkgo Biloba relaxes blood vessels, and when paired with the metabolic benefits of ALA, it helps manage diabetic complications and improves vascular function.

ALA has a unique ability to recycle other antioxidants like vitamin C and E, and when paired with the flavonoids in Ginkgo, it strengthens the body’s antioxidant defenses.

Resveratrol & Ginkgo Biloba Leaf Extract

Combining Ginkgetin (a compound in Ginkgo) and Resveratrol significantly reduces VEGF (Vascular Endothelial Growth Factor) levels, crucial for inhibiting tumor blood vessel growth, with efficacy similar to some pharmaceutical agents.

Both compounds together offer cardio protection against diet-induced dysfunction by combating oxidative stress and fibrosis.

The combination holds potential for managing neurocognitive disorders by reducing oxidative stress and regulating neuroinflammation.

INGREDIENTS:

Alpha Lipoic Acid, Resveratrol 99%, Coleus Forskohlii Extract 10%, Ginkgo Biloba Leaf Extract 20:1, Bioperine